Costus speciosus (Kann Kongo) : medicinal properties in alcoholic extraction

Costus speciosus (Kann Kongo) — family Costacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The monograph draws on 51 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Liver disorders : Plant part used: Rhizome.
   According to Verma N (2009): The extract registered a significant fall in the levels of serum glutamyl oxalacetic acid transaminase (SGOT), serum glutamyl pyruvate transaminase (SGPT), alkaline phosphatase (ALKP), serum bilirubin (SBLN) & liver inflammation supported by histopathological studies on liver, thus exhibited a significant hepatoprotective activity. The hepatoprotective activity of the ethanolic extract of the rhizomes of Costus speciosus (Koenig) Sm. According to NAIR SVG (2014): speciosus on the growth of human hepatocellular carcinoma (HepG2) cell & understand possible mechanisms of its action.
2. Dyslipidaemia : Plant part used: Rhizome. Documented pharmacological profile: Simvastatine-like.
3. Type II diabetes mellitus : Plant part used: Rhizome. Documented pharmacological profile: Glibenclamide-like.
   According to Ali HA (2014): speciosus) root ethanolic extracts (CSREt) by assessing its action on insulin synthesis & glucose catabolic enzyme gene expression & activities in streptozotocin (STZ) diabetic rats. Four groups of STZ diabetic animals were given oral CS (CSREt) in doses of 200, 400, & 600 mg/kg body weight, & 600 µg/kg body weight of the standard drug Glibenclamide for 4 weeks. According to Reavathy J (2014): Our experimental findings with respect to the mechanism of action of extract in alloxan induced diabetic rats suggest that it enhances insulin secretion by the islets of Langerhans, enhances peripheral glucose utilization & increases serum protein levels.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Saga70 without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.