Croton tiglium (Ti piyon-dend) : medicinal properties in alcoholic extraction

Croton tiglium (Ti piyon-dend) — family Euphorbiacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 6 indications in alcoholic extraction for this species. The monograph draws on 52 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Dermatophytosis : Plant part used: Fruit. Documented pharmacological profile: Amphotericine B-like.
   According to Lin HC (2016): rubrum, & Epidermophyton floccosum. Dermatophytosis, which is caused mainly by genera of Trichophyton, Epidermophyton, & Microsporum, is a frequent dermatological problem in tropical and subtropical countries. According to Shahid M (n.d.): Antifungal & antibacterial activities were determined after each purification step.
2. Convulsion, epileptic fit : Plant part used: Seed. Documented pharmacological profile: Valproate de sodium-like.
   According to Raghunandan Mudium (2014): However, anticonvulsant effect was less compared to sodium valproate. The hydroalcoholic seed extract of CT (250 & 500mg/kg) was studied for its anticonvulsant effect using sodium valproate (200mg/kg) as standard & distilled water as control.
3. Constipation : Plant part used: Fruit. Documented pharmacological profile: Bisacodyl-like.
   According to Akbar S (2020): Ethanol seed extract at a dose of 0.06 mL/30 g was effective as laxative in 100% mice, with an ED50 of 0.027 mL; the laxative effect was partially blocked by atropine. In Ayurveda, seeds & seed oil are used in the treatment of constipation, fever, intestinal worms, anasarca, ascites, enlargement of abdominal viscera, tympanites, calculous affections, colic, & gout. According to Hu Jing (2012): Croton oil is the fruit oil of Croton tiglium L., which is well known in folk medicine for the treatment of gastrointestinal (GI) diseases, including constipation, abdominal pain, peptic ulcer, and intestinal inflammation for a long period.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Vinayaraj without modification (CC BY-SA 3.0). License : CC BY-SA 3.0.