Daucus carota (Kawôt) : medicinal properties in alcoholic extraction

Daucus carota (Kawôt) — family Apiacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 13 indications in alcoholic extraction for this species. The monograph draws on 58 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Whole plant. Documented pharmacological profile: Cisplatine-like.
   According to Zeinab RA (2011): carota umbels on 7, 12-dimethyl Benz (a) anthracene (DMBA)-induced skin cancer in mice. Tumor appearance, incidence, yield & volume were compared with those of a non-treated control group. According to ALKHATIB MH (2019): Forty female Swiss Albino mice bearing Ehrlich ascites carcinoma (EAC) were split into four groups (n =10).
2. High blood pressure, oedema, fluid retention : Plant part used: Fruit. Documented pharmacological profile: Furosemide-like.
   According to Gilani AH (2000): Intravenous administration of these compounds caused a dose-dependent (1-10 mg/kg) fall in arterial blood pressure in normotensive anaesthetised rats. These results indicate that DC-2 & DC-3 may be acting through blockade of calcium channels & this effect may be responsible for the blood pressure lowering effect of the compounds observed in the in vivo studies. According to Al-Snafi A (n.d.): The pharmacological studies revealed that the plant possessed cytotoxic, antioxidant, antidiabetic, antimicrobial, smooth muscle relaxant, hypotensive effect and decrease intraocular pressure, gastroprotective, nephroprotective, hepatoprotective, cardioprotective antidepressant memory enhancement, anti-inflammatory, reproductive, wound healing and hear induction and many other effects.
3. Hypercholesterolaemia, hypertriglyceridaemia, hyperlipidaemia, atherosclerosis : Plant part used: Seed. Documented pharmacological profile: Lovastatine-like.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

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