Euphorbia neriifolia (Elaikalli) : medicinal properties in alcoholic extraction

Euphorbia neriifolia (Elaikalli) — family Euphorbiacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 20 indications in alcoholic extraction for this species. The monograph draws on 50 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Arthritis, osteoarthritis, rheumatism, oedema : Plant part used: Stem. Documented pharmacological profile: Indometacine-like.
   According to Kalpesh G (2009): The hydro-alcoholic extract was studied for their anti-inflammatory activity by using carrageenan-induced hind paw edema in rats and the mean increase in paw volume & % inhibition in paw volume were measured plethysmometrically at different time intervals after carrageenan (1% w/v) injection. The hydro-alcoholic extract showed a greater anti-inflammatory and analgesic effect when compared with the standard drugs, indomethacin & Diclofenac sodium respectively. According to SAMAR KB (2009): This report illustrates the spectrum of ocular inflammation caused by accidental inoculation of latex of Euphorbia plant.
2. Cancer : Plant part used: Aerial parts. Documented pharmacological profile: Cisplatine-like.
   According to Author (2012): The cancer treatable by the compound of formula (I) is chronic myelogenous leukemia (CML), oesophageal cancer or pancreatic cancer. The triterpenoids are useful as lead compounds for manufacturing a medicament or a pharmaceutical composition for treating cancer; whereas the ingol diterpenes are useful as lead compounds for manufacturing a medicament or a pharmaceutical composition for treating thrombocytopaenia. According to UPADHIYAYA C (2017): Antitumor activity of acetone extract was investigated against DLA induced ascites tumor in mice.
3. Type II diabetes mellitus : Plant part used: Stem. Documented pharmacological profile: Glibenclamide-like. Mentioned synergistic association: Glibenclamide.
   According to MANSURI MI (2013): MANSURI MI et al, Evaluation of Antidiabetic and Antihyperlipidemic Activity of Euphorbia Neriifolia L in High Fat Diet- Streptozotocin Induced Type-2 Diabetic Model, Int Jl for Pharmaceut Res Scholars, 2(1-1) :83-9, 2013-Abstract Euphorbia neriifolia is traditionally used to treat diabetes mellitus. The present study was undertaken to evaluate the antidiabetic & antihyperlipidemic effect in high fat diet-streptozotocin (HFD-STZ) induced type-2 diabetic rats. According to Mansuri MI (2012): Purpose of the study was to evaluate the antidiabetic activity of ethanolic extracts of leaves of E neriifolia in alloxan induced diabetic rats.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo de Dinesh Valke sans modification. License : CC BY-SA 2.0.