Gardenia jasminoides (Cape jasmine) : medicinal properties in alcoholic extraction

Gardenia jasminoides (Cape jasmine) — family Rubiacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 9 indications in alcoholic extraction for this species. The monograph draws on 141 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Depression : Plant part used: Fruit. Documented pharmacological profile: kétamine-like. Mentioned synergistic association: CYPERUS ROTUNDUS-L, Ligustrum sp, Actralocydes lancea, Massa fermentata.
   Selon Tao W (2014) : Optimization of supercritical fluid extraction of oil from the Gardenia jasminoides & its antidepressant activity, Molecules, 19 (2014) :19350-60 CrossRefGoogle Scholar. Selon Chen L (2020) : Various pharmacological properties, such as a beneficial effect on the nervous, cardiovascular & digestive systems, hepatoprotective activity, antidepressant activity, & anti-inflammatory activity, were also validated in vitro & in vivo.
2. Gastritis, peptic ulcer : Plant part used: Fruit. Documented pharmacological profile: Cimétidine-like.
   Selon Lee JH (2009) : In this study we investigated the effects of Gardenia jasminoides Ellis (GJE) extract & its constituents, such as ursolic acid & genipin, on gastritis in rats & the growth of human gastric cancer cells. The genipin & ursolic acid inhibited significant HCl/ethanol-induced gastric lesions. Selon Wang M (2019) : In this study we investigated the effects of Gardenia jasminoides Ellis (GJE) extract & its constituents, such as ursolic acid & genipin, on gastritis in rats & the growth of human gastric cancer cells.
3. Osteoarthritis, arthritis, rheumatism, oedema : Plant part used: Fruit. Documented pharmacological profile: Aspirine-like, Indometacine-like.
   Selon Nam K.N (2010) : Genipin has recently been reported to have diverse pharmacological functions, such as antimicrobial, antitumor, and anti-inflammatory effects. Furthermore, genipin effectively inhibited microglial activation in a mouse model of brain inflammation. Selon Fu Y (2012) : These results suggest that geniposide exerts an anti-inflammatory property by down-regulating the expression of TLR4 up-regulated by LPS.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Mokkie without modification (CC BY 4.0). License : CC BY 4.0.