Guaiacum officinale (Gayak) : medicinal properties in alcoholic extraction

Guaiacum officinale (Gayak) — family Zygophyllacées.

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The monograph draws on 14 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Fruit. Documented pharmacological profile: Cisplatine-like.
   Selon Sarkar A (2014) : Design: Rheumatoid arthritis (RA) was induced in male albino rats by Freund's complete adjuvant (FCA) at a dose of (0.25 mg heat killed Mycobacterium tuberculosis/ml of emulsion). Selon Duwiejua M (1994) : At 200 mg kg-1 administered before the induction of adjuvant arthritis, P. bistorta significantly inhibited both the acute & chronic phases of the adjuvant-induced rat paw swelling, while G.
2. Oxidative stress : Plant part used: Fruit. Documented pharmacological profile: Acide ascorbique-like.
3. Adjuvant treatment for diabetic foot : Plant part used: Sheet. Documented pharmacological profile: Neosporine-like.
   Selon Bahado-Singh PlS (2014) : & G officinale in an excision wound model of normal & streptozotocin induced type I diabetic rats. One of the major challenges faced by people living with diabetes is the treatment & management of diabetic sores & ulcers. Selon Sarkar A (2014) : Design: Rheumatoid arthritis (RA) was induced in male albino rats by Freund's complete adjuvant (FCA) at a dose of (0.25 mg heat killed Mycobacterium tuberculosis/ml of emulsion).

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Forest & Kim Starr without modification (CC BY 4.0). License : CC BY 4.0.