Guazuma ulmifolia (Bwa-dôm) : medicinal properties in alcoholic extraction

Guazuma ulmifolia (Bwa-dôm) — family Sterculiacée.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 15 indications in alcoholic extraction for this species. The monograph draws on 28 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Documented pharmacological profile: Doxorubicine-like.
   Selon -LUKMAN M (2014) : These extracts were assessed using HeLa cell cancer (Human cervix cancer) & doxorubicin was used as the positive control. Dose-dependent studies revealed IC50 of 113.61±0.12 µg/mL, 174.90±1.22 µg/mL & 126.05±2.43 µg/mL for e-GA, e-GU & e-CO on HeLa cell cancer, respectively & correlated with treatment of cancer. Selon Auteur (2015) : Jati Belanda ethanolic extract also could induce apoptosis in the Breast cancer cell (MCF-7) & cervical cancer cell (HeLa).
2. Bleeding, haemorrhoids, haematuria : Plant part used: Sheet.
   Selon Sulistiyani P (2017) : This is a preliminary research report on the use of Caenorhabditis elegans as a model to establish anti-obesity screening assay of the natural plant resources. Selon Alonso-Castro AJ (2008) : Alonso-Castro AJ et al, the anti-diabetic properties of Guazuma ulmifolia Lam are mediated by the stimulation of glucose uptake in normal & diabetic adipocytes without inducing adipogenesis, J of Ethnopharmacol, 118(2): 252–6, 2008.
3. Obesity, adipocytosis : Plant part used: Sheet. Documented pharmacological profile: Orlistat-like, Xenical-like. Mentioned synergistic association: association synergique avec MURRAYA PANICULATA (Linn) Jack. (Feuille).

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Dick Culbert without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.