Gynandropsis gynandra (White Akaya) : medicinal properties in alcoholic extraction

Gynandropsis gynandra (White Akaya) — family Capparacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 15 indications in alcoholic extraction for this species. The monograph draws on 109 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Documented pharmacological profile: Doxorubicine-like.
   Selon Bata A (2011) : Twenty four hours of last dose & eighteen hours of fasting, the mouse were sacrificed & antitumor effect of the all fractions were assessed by evaluating tumor volume, viable & nonviable tumor cell count, tumor weight, biochemical, enzymatic and hematological antioxidant parameters of EAC bearing host. It’s anticancer and antioxidant activity is already proved by our research groups; therefore we started to perform column chromatography of methanol extract over silica-gel. Selon Dhandayuthapani S (2019) : These results indicate that GG extract could potentially modulate the cancer marker enzymes & thus could elicit suppressive activity on tumour growth in AFB1-induced male albino rats.
2. Dyslipidaemia : Plant part used: Sheet. Documented pharmacological profile: Atorvastatine-like.
   Selon Mallikarjuna G (2018) : Hyperlipidemia model was induced by administering dexamethasone (10mg/kg, b.wt.,s.c.) in rats with significant imbalance in the in serum lipid profiles such as TC, TG, VLDL-C, LDL-C, HDL-C levels along with increase in atherogenic index. The present study was aimed at investigating hypolipidemic activity of Cleome gynandra L. Selon SHAIK K (2013) : Other parameters such as serum cholesterol, triglycerides, HDL, LDL, VLDL levels were also estimated.
3. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Amoxicilline-like.
   Selon Borgio JF (2007) : Results: Bacterial cultures of Escherichia coli & Staphylococcus aureus were highly susceptible to the acetone extracts of all the five parts of G. Conclusion: The active antimicrobial ingredients in G. Selon Ajaiyeoba EO (2000) : Chev.) were screened phytochemically for the presence of secondary metabolites & for in vitro antibacterial & antifungal properties respectively.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Ton Rulkens without modification. License : CC BY-SA 2.0.