Ipomoea aquatica (Zépina-dlo) : medicinal properties in alcoholic extraction

Ipomoea aquatica (Zépina-dlo) — family Convolvulacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 14 indications in alcoholic extraction for this species. The monograph draws on 63 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Type II diabetes mellitus : Plant part used: Aerial parts. Documented pharmacological profile: Metformine-like.
   Selon Malalavidhane TS (2003) : The present study was designed to investigate the oral hypoglycaemic activity of IA in streptozotocin induced diabetic Wistar rats, & Type II diabetic patients. Experimental diabetes was induced with streptozotocin in Wistar rats. Selon MALALAVIDHANE TS (2003) : The present study was designed to investigate the oral hypoglycaemic activity of IA in streptozotocin induced diabetic Wistar rats, & Type II diabetic patients.
2. Oxidative stress : Plant part used: Sheet. Documented pharmacological profile: BHT-like.
   Selon Dewanjee S (2015) : Dewanjee S et al, Water Spinach, Ipomoea aquatica (Convolvulaceae), Ameliorates Lead Toxicity by Inhibiting Oxidative Stress & Apoptosis, PLoS One. Selon Bokolo B (2019) : Plasma was extracted from blood & evaluated for renal function indices while kidneys were evaluated for oxidative stress markers & histology.
3. Heart disease : Plant part used: Sheet. Documented pharmacological profile: Prazocine-like.
   Selon Khayungarnnawee A (2018) : The data showed that IAE had no effect on blood pressure and heart rate in anesthetized rats after injected the extract solution. However, IAE showed suppression of the NA-mediated aortic contraction in a dose dependent manner. Selon MALALAVIDHANE TS (2003) : The results revealed that consumption of the shredded, fresh, edible portion of IA for one week, effectively reduced the fasting blood sugar level of streptozotocin-induced diabetic rats (p = 0.01).

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Eric Guinther without modification (CC BY 4.0). License : CC BY 4.0.