Kigelia africana (Sausage maker) : medicinal properties in alcoholic extraction

Kigelia africana (Sausage maker) — family Bignoniacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 18 indications in alcoholic extraction for this species. The monograph draws on 78 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Fruit.
   Selon Olufemi AE (2017) : Conclusion: This study revealed the potential of ethanol extracts of K africana stem bark, fruit a leaf to reverse leukaemic effects in benzène-induced leukemia bearing Wistar rats and this suggest that the extracts might be promising natural, non-Toxic and anticancer agents. Leukaemic rats were administered with 100 mg/mL contained in 0.5 mL stem bark, 0.5 mL fruit & 0.2 mL of the leaf extract orally by gavage using oral cannula once daily post leukemia induction for four weeks. Selon Momekova D (2012) : Results: TME displayed prominent cytotoxicity against a panel of human tumor cell lines.
2. Bacterial infection : Plant part used: Stem bark. Documented pharmacological profile: Oxytetracycline-like, Amoxicilline-like.
   Selon Auteur (2016) : Staphylococcus aureus, Proteus vulgaris, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae & Citrobacter amalonaticus by agar-disc diffusion method. In vitro antibacterial activity of extracts was tested against six bacterial strains viz. Selon Tyagi A (2011) : Tyagi A et al, Isolation & antibacterial susceptibility testing of multi drug resistant Pseudomonas aeruginosa causing urinary tract infection.
3. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Gentamycine-like.
   Selon OLUBUKOLA JO (2011) : Methodology: Crude extracts of fresh leaves of Ocimum gratissimum, Psidium guajava, Vernonia amygdalina, Kigelia africana, Azadirachta indica, Pistia stratiotes, Euphorbia hirta, bulb of Allium sativum & Zingiber officinale & Curcuma longa, were evaluated using the agar diffusion assay method & minimal inhibitory concentration (MIC) to determine the antibacterial activities against Vibrio Cholerae, Escherichia Coli & salmonella Sp. Was not inhibited by ethanolic extracts of Euphorbia hirta & Curcuma longa, both water and ethanolic extracts of others inhibited the growth of Vibrio Cholerae, Escherichia coli & salmonella Sp to varying degree. Selon Binutu OA (1996) : Binutu OA et al, Antibacterial & Antifungal compounds from Kigelia pinnata, Planta Med.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Vijayanrajapuram without modification (CC BY 4.0). License : CC BY 4.0.