Lactuca sativa (Leti) : medicinal properties in alcoholic extraction

Lactuca sativa (Leti) — family Asteracées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The monograph draws on 41 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Amoxicilline-like.
   Selon MLADENOVIC JD (2013) : The antimicrobial activity of the lettuce extract, was tested with bacteria from clean cultures Staphylococcus aureus ATCC 25923, Klebsiella pneumoniae ATCC13883, Escherichia coli ATCC 25922, Proteus vulgaris ATCC13315, Proteus mirabilis ATCC14153, Bacillus subtilis ATCC6633, and fungi Candida albicans ATCC10231 & Aspergillus niger ATCC16404. The smallest susceptibility to the ethanolic extract of lettuce was exhibited by the bacteria S aureus & P vulgaris (MIC=78,125 g/ml), while the other selected bacteria and fungi showed higher susceptibility (MIC=39,1 g/ml). Selon Zdravkovic J (2012) : In order to determinate the antimicrobial activity of the extract, clean cultures originating from The Institute of Virology, Vaccines & Sera Torlak: Staphylococcus aureus ATCC 25923, Klebsiella pneumoniae ATCC13883, Escherichia coli ATCC 25922, Proteus vulgaris ATCC13315, Proteus mirabilis ATCC14153, Bacillus subtilis ATCC6633, Candida albicans ATCC10231, Aspergillus niger ATCC16404 have been used.
2. Pain, hyperalgesia : Plant part used: Sheet. Documented pharmacological profile: Morphine-like.
   Selon Ismail H (2015) : Results: Interestingly, the extracts & the cell suspension exudate showed dual inhibition by reducing pain & inflammation. The results indicated that the aqueous extracts of leaf exhibited highest analgesic & anti-inflammatory activities followed by leaf MC, cell suspension exudate, seed aqueous & seed MC extracts. Selon Hammad I (2015) : Interestingly, the extracts and the cell suspension exudate showed dual inhibition by reducing pain & inflammation.
3. Fungal infection : Plant part used: Sheet. Documented pharmacological profile: Nystatine-like.
   Selon MLADENOVIC JD (2013) : The antimicrobial activity of the lettuce extract, was tested with bacteria from clean cultures Staphylococcus aureus ATCC 25923, Klebsiella pneumoniae ATCC13883, Escherichia coli ATCC 25922, Proteus vulgaris ATCC13315, Proteus mirabilis ATCC14153, Bacillus subtilis ATCC6633, and fungi Candida albicans ATCC10231 & Aspergillus niger ATCC16404. The antimicrobial activity was determined by microdilution method (MIC). Selon Ezdiri HL (2011) : Antioxidant, antibacterial & antiviral effects of aqueous & methanol extracts of Lactuca sativa var longifolia leaves were investigated.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by DeFacto without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.