Lagerstroemia speciosa (Jèstram) : medicinal properties in alcoholic extraction

Lagerstroemia speciosa (Jèstram) — family Lythracées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 19 indications in alcoholic extraction for this species. The monograph draws on 85 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Mentioned synergistic association: 5-Fluoro-Uracile.
   Selon LEE HS (2017) : Thus, these data indicate that CRA enhances the anticancer activities of 5FU via mTOR inhibition in SNU620 human gastric carcinoma cells. In the present study, the anticancer effects of 5FU combined with corosolic acid (CRA) were determined in SNU620 human gastric carcinoma cells and the underlying mechanisms were examined. Selon Singh R (2020) : We investigated the cytotoxic potentials of ethanolic Banaba leaves extract (EBLE) against human hepatocellular carcinoma (HepG2) cell line.
2. Bacterial infection : Plant part used: Fruit. Documented pharmacological profile: Kanamycine-like.
   Selon FAYSAL M (2016) : In antibacterial test, ethanolic extract (500 µg /dise) showed zone of inhibition against Staphylococcus epidermis, Enterococci, Escherichia coli and Staphylococcus saprophyticus diameter of zone were respectively 7, 6, 6 and 6. The zone of inhibition (mm) produced by the ethanol extract at the concentration of 500 μg/disc and Kanamycin at the concentration of 30μg/disc against different bacterial strains. Selon Laruan LR (2013) : Laruan LR et al, Phytochemical & antibacterial study of Lagerstroemia speciosa (L.) Pers.
3. Hepatitis, cirrhosis, fatty liver disease : Plant part used: Flower. Documented pharmacological profile: Silymarine-like.
   Selon Singh RT (2021) : This study investigates the hepatoprotective effect of ethanolic LS leaves extract (EBLE) against simultaneously administered INH- & DDS-induced hepatotoxicity in rats. Drug-induced liver injury is a common cause of acute liver failure. Selon Suzuki Y (1999) : No effects on the serum lipids were observed, but the mice fed LS-extract showed a significant decrease, to 65% of the control level in total hepatic lipid contents.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Vengolis without modification (CC BY 4.0). License : CC BY 4.0.