Laportea aestuans (Zôti) : medicinal properties in alcoholic extraction

Laportea aestuans (Zôti) — family Urticacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 11 indications in alcoholic extraction for this species. The monograph draws on 42 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Chloramphenicol-like.
   Selon Simaremare ES (2017) : The aim of the study was to determine the activity of antibacteria of LA against Escherichia coli, Staphylococcus aureus & Salmonella typhi. Extract was made in 250, 500, 750, 1000 ppm, with chloramphenicol as a control positive, while the test of antibacterial activity was done by disc diffusion method. Selon OLEYODE G (2011) : The oils showed appreciable antimicrobial activity -against Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Salmonella typhi, Candida albicans, Rhizopus stolon, Aspergillus niger & Penicillium notatum at 200mg/ml when compared to standards; gentamicin for bacteria & tioconazole for fungi.
2. Osteoarthritis, arthritis, rheumatism, oedema : Plant part used: Sheet. Documented pharmacological profile: Diclofenac-like.
   Selon Ashidi J (2017) : Similar doses were given to test its anti-inflammatory activity but 10 mg/kg of diclofenac sodium was given as the positive control. This study evaluates the analgesic & anti-inflammatory potential of the ethanol extract of the leaves of LA using hot-plate induced analgesia and carrageenan-induced acute inflammatory model in Albino Wistar rats (120g-160g). Selon Simaremare ES (2018) : Then ELA was evaluated analgesic with tail flick test & anti-inflammatory effect with carrageen-induced paw edema with 0.3 g/kg, 0.6g/kg, & 1.2g/kg dose on white male rat.
3. Pain, hyperalgesia : Plant part used: Sheet. Documented pharmacological profile: Ibuprofène-like.
   Selon Simaremare ES (2018) : The objective of this study aims to screen active compound chemical, determine LC50, IC50, & analgesic-antiinflammatory activity effect of ethanolic extract from L. Laportea aestuans (Linn.) Chew as original plant from Papua has been using for pain relief as traditional medication in the local community widely. Selon Ashidi J (2017) : This study evaluates the analgesic & anti-inflammatory potential of the ethanol extract of the leaves of LA using hot-plate induced analgesia and carrageenan-induced acute inflammatory model in Albino Wistar rats (120g-160g).

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Alexey Yakovlev without modification (CC BY 4.0). License : CC BY 4.0.