Leonitis nepetifolia (Soldier’s pompom) : medicinal properties in alcoholic extraction

Leonitis nepetifolia (Soldier’s pompom) — family Lamiacées.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 9 indications in alcoholic extraction for this species. The monograph draws on 22 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Vomiting : Plant part used: Sheet. Documented pharmacological profile: Metoclopramide-like.
   Selon KUMAR JB (2016) : Ethanol extract of 200 mg/kg inhibited the retches up to 73.761%, which inhibited emesis to an extent equal to Metoclopramide at 50mg/kg. Results: The results reveal the presence of bioactive constituents comprising alkaloids, flavonoids, phenolics, tannins, glycosides, steroids and saponins in different solvents and also have antiemetic potential comparable with that of the reference drug Metoclopramide.
2. Cancer : Plant part used: Aerial parts. Documented pharmacological profile: 5-Fluoro-Uracile-like.
   Selon Gurunagarajan S (2010) : Tumor was induced intraperitoneally using Ehrlich Ascites Carcinoma cells (1×106 cells/mouse). Br (EELN) on Ehrlich Ascites Carcinoma cell lines. Selon Veerabadran U (s.d.) : To investigate the antioxidant & antiproliferative potential of Leonotis nepetifolia leaves.
3. Inflammation, rheumatic pain : Plant part used: Flower. Documented pharmacological profile: Diclofenac-crème-like.
   Selon Manocha N (2012) : Manocha N et al, Anti-inflammatory & antirheumatic activity of the chemical constituents of Leonotis nepetifolia capitulum. Selon Parra-Delgado H (2004) : Several extracts of aerial parts of Leonotis nepetaefolia showed anti-inflammatory activity on TPA-induced edema model. Although the presence of leonotinin is in agreement with previous phytochemical studies of this species, this is the first time that its anti-inflammatory activity is determined.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Burkhard Mücke without modification (CC BY 4.0). License : CC BY 4.0.