Lippia dulcis (Zèb-dous) : medicinal properties in alcoholic extraction

Lippia dulcis (Zèb-dous) — family Verbenacées.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The monograph draws on 17 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Arthritis, osteoarthritis, rheumatism : Plant part used: Aerial parts. Documented pharmacological profile: Indometacine-like.
   Selon PEREZ S (2005) : Lippia dulcis hexane & ethanol extracts were tested for its anti-inflammatory activity in several animal models. Hexane extract showed to but the ethanol extract at doses of 400 mg/kg produced significant inhibition of carrageenan-induced paw oedema and reduced the ton pellet-induced granuloma, Moreover, the topical application of 0.5 mg/ear of this extract inhibited the edema induced with TPA an effect which is of less intensity than that produced by indomethacin at the same dose. Selon Perez S (2005) : ippia dulcis hexane & ethanol extracts were tested for its anti-inflammatory activity in several animal models.
2. Bacterial infection : Plant part used: Aerial parts.
   Selon CACERES A (1993) : Extracts were obtained with three solvents of different polarity (n-hexane, acetone and alcohol) & the in vitro activity was demonstrated against Enteropathogenic Escherichia coli, Salmonella enteritidis & Shigella flexneri. The plants with antibacterial activity are discussed. Selon COMPADRE CM (1986) : Hernandulcin was nontoxic when administered orally to mice, & it did not induce bacterial mutation,.
3. Respiratory conditions : Plant part used: Aerial parts.
   Selon Gornemann T (2008) : (Verbenaceae) that is traditionally used in the treatment of cough, colds, bronchitis, asthma, & colic in Middle America for antispasmodic activity.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo from the Traditional Martinique Pharmacopoeia.