Microtea debilis (Maripérinn’) : medicinal properties in alcoholic extraction

Microtea debilis (Maripérinn’) — family Phytolaccacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 3 indications in alcoholic extraction for this species. The monograph draws on 11 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cellulite : Plant part used: Whole plant. Mentioned synergistic association: de l’eau oxygénée.
   Selon Bai N (2011) : Compounds 2, 4, 6, & 7 showed moderate anti-proliferative activity against COLO-205 cells with IC50 values of 7.1, 13.1, 6.1, & 6.8 μM, respectively. All isolates were tested for cytotoxicity in human cancer cell lines (Hep G2, COLO 205, & HL-60) & anti-inflammatory activities in LPS-treated RAW264.7 macrophages.
2. Osteoarthritis, arthritis, rheumatism, oedema : Plant part used: Aerial parts.
   Selon Bai N (2011) : All isolates were tested for cytotoxicity in human cancer cell lines (Hep G2, COLO 205, & HL-60) & anti-inflammatory activities in LPS-treated RAW264.7 macrophages. Selon Mahmood A (2019) : It is an active flavone that possessed a number of potent pharmacological activities such as anti-oxidant, anti-microbial, anti-oxidant, anti-microbial, anti-cancer, anti-inflammatory, anti-diabetic & many more. This review article shows that the cirsimaritin contains important pharmacological properties including antioxidant, antiinflammatory, antimicrobial, antidiabetic, anticancer, antagonistic properties, neurological effects, cardiovascular, & hepatoprotective properties.
3. Cancer : Plant part used: Aerial parts.
   Selon Pathak G (2021) : Its antiproliferative potential has been explored in breast & gall bladder cancer cell lines. However, no reports are available on skin & squamous lung carcinoma. Selon Khan MK (2013) : Khan MK et al, Dietary phytochemicals as potent chemo-therapeutic agents against breast cancer: Inhibition of NF-κB pathway via molecular interactions in rel homology domain of its precursor protein p105.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Anonyme973 without modification (CC BY 4.0). License : CC BY 4.0.