Ocimum micranthum (Ti-fonbazen) : medicinal properties in alcoholic extraction

Ocimum micranthum (Ti-fonbazen) — family Lamiacées.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The monograph draws on 43 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Amikacine-like.
   Selon Blessy-Jacob BP (2022) : The antibacterial activity of the formulation F2 was determined at 60 mg/ml by MIC using test tube dilution method. Selon Caamal-Herrera IO (2018) : Methods: The minimal inhibitory concentration (MIC) of essential oil & aqueous & ethanolic extracts of OM leaves against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa & Candida albicans was determined using the microdilution technique. In the case of S aureus, B subtilis, & P aeruginosa, the MIC of the aqueous & ethanolic extract was 125 μL/mL.
2. Fungal infection : Plant part used: Aerial parts. Documented pharmacological profile: Fluconazole-like.
   Selon Zaidi K.U (2018) : Methanolic extract of stem of OS in combination with fluconazole gave indifferent antifungal results (FIC=1.0-4.0). Synergistic antimicrobial activity was found when methanolic extract of leaves of OS was used in combination with fluconazole against C. Selon Tacchini M (2022) : syringae & a moderate effect against clinical Candida strains, with possible synergism in association to fluconazole against the latter microorganisms.
3. Glycation, prevention of the effects of the Maillard reaction (Advanced Glycation
   End-products – AGEs) : Plant part used: Whole plant. Documented pharmacological profile: Aminoguanidine-like.
   Selon Dzib-Guerra WD (2016) : MATERIALS & METHODS: ethanolic extracts of leaves, stems & roots of nine medicinal plants, together with their traditional preparations, were prepared & tested for their anti-AGE & antioxidant activities using the inhibition of advanced glycation end products & DPPH radical scavenging assays, respectively. Formation & accumulation of advanced glycation end-products (AGE) is recognized as a major pathogenic process in diabetic complications, atherosclerosis & cardiovascular diseases. Selon Kelm MA (2000) : Anti-inflammatory activity or cyclooxygenase inhibitory activity of these compounds were observed.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Alex Popovkin without modification (CC BY 4.0). License : CC BY 4.0.