Passiflora edulis (Marakoudja) : medicinal properties in alcoholic extraction

Passiflora edulis (Marakoudja) — family Passifloracées.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The monograph draws on 59 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Documented pharmacological profile: Tamoxifène-like, Letrozole-like.
   Selon Fotsing S (2023) : Fotsing S et al, Breast cancer cell growth arrest & chemopreventive effects of Passiflora edulis Sims (Passifloraceae) ethanolic leaves extract on a rat model of mammary carcinoma, Pharmacol, 311:116408.2023-Abstrtact: Despite various prevention & treatment measures, the incidence & mortality due to breast cancer has been increasing globally. Aim of the study: To assess the anti-breast cancer activity of the ethanolic extract of PE leaves in vitro & in vivo. Selon Aguillón-Osma (2013) : To investigate the antioxidant & antiproliferative activity of ethanolic & aqueous extracts from leaves & fruits of Passiflora edulis.
2. Anxiety, insomnia, nervousness : Plant part used: Sheet. Documented pharmacological profile: Diazépam-like.
   Selon Deng J (2010) : Anxiolytic & sedative activities of Passiflora edulis f. Selon PETRY RD (2001) : The anxiolytic activity of Hydroethanol extracts of P. The extracts presented anxiolytic activity in dosages around 50, 100 & 150 mg/kg.
3. Viremia : Plant part used: Sheet. Mentioned synergistic association: Acyclovir.
   Selon Jabareen A (2013) : In the present study we examined, in vitro, the antiviral potential of aqueous & ethanolic leaf extracts on herpes simplex viruses 1 & 2 (HSV-1, HSV-2) & on Varicella-Zoster virus (VZV). Most prominent antiviral activity was obtained when the 80%-MeOH fraction was added during the infection, or when it was incubated with the virus particles prior to infection. Selon Ripa F (2009) : The petroleum ether & chloroform fractions of ethanol extract of leaf & stem from the plant Passiflora edulis (Fam: Passifloraceae) was subjected to antioxidant, antibacterial & cytotoxic activity.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo from the Traditional Martinique Pharmacopoeia.