Pennisetum purpureum (Zèb-léfan) : medicinal properties in alcoholic extraction

Pennisetum purpureum (Zèb-léfan) — family Poacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The monograph draws on 38 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Pain, hyperalgesia : Plant part used: Sheet. Documented pharmacological profile: Aspirine-like, Acetaminophène-like.
   Selon Igbokwe E (2015) : The study is aimed at evaluating the analgesic activity of the ethanol extract of PP in experimentally induced acetic acid writhing in mice. Flavoids, saponin & glycosides are known for their ability to inhibit pain.
2. Oxidative stress : Plant part used: Sheet. Documented pharmacological profile: Acide gallique-like.
   Selon Verma S (2017) : Pearl millet’s high flavonoid content has incredible anti-inflammatory & anti-oxidant properties to reduce oxidative stress and inflammation, common pathologies of neurodegenerative diseases (NDs). Selon Olorunsanya AO (2011) : Olorunsanya AO et al, Effect of bamboo (Bambusa valgaris) & elephant grass (Pennisetum purpureum) leaf extracts on oxidative stability of cooked & raw broiler meat.
3. Cancer : Plant part used: Sheet. Documented pharmacological profile: Docetaxel-like.
   Selon Flora TM (2018) : The most cytotoxic extracts were then further tested on a panel of 8 human cancer cell lines, including various MDR phenotypes. They were further tested in 8 other cell lines as well as in normal AML12 hepatocytes. Selon Oluwefemi Adekelo Ojo (2022) : purpureus shoots (AECPS) & the mechanism of action on pancreatic ß-cell dysfunction.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Ping an Chang without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.