Periplaneta americana (Ravèt) : medicinal properties in alcoholic extraction

Periplaneta americana (Ravèt) — family Blattidés.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 11 indications in alcoholic extraction for this species. The monograph draws on 107 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Whole body. Documented pharmacological profile: Cyclophosphamide-like.
   Selon Zhao Y (2017) : The main mechanisms of its anti-tumor effects include suppression of tumor cell growth, induction of cell cycle arrest & tumor cell apoptosis, inhibition of angiogenesis, enhancement of immunity, & reversal of tumor drug resistance. In this review, the research progress on the anti-tumor effects of Pa was summarized. Selon NI L (2020) : to investigate the effects of Periplaneta americanaextract on the proliferation & apoptosis of human non-small cell lung cancer A 549 cells as well as its possible mechanism.
2. Infected wound, injury, incision : Plant part used: Whole body. Documented pharmacological profile: Povidone iodine-like.
   Selon Chen KH (2009) : Materials & methods: Wistar rats receiving total body irradiation of 60-Co γ-rays alone or with combined radiation & skin wound injury were used in this study. Conclusions: W11-a12 showed a protective effect on hematopoiesis after total body irradiation & could increase the inflammatory cells in wounded tissues at the initiation stage after irradiation, which will benefit the management of combined radiation & skin wound injury. Selon Song Q (2017) : Periplaneta americana extracts (PAEs) exhibit wound healing properties.
3. Ulcerative colitis : Plant part used: Whole body. Documented pharmacological profile: Sulfasalazine-like.
   Selon Lu K (2021) : Acute colitis mice model was established, the acute toxicity & anti-inflammatory activity were tested in vivo. OPA exhibited anti-inflammatory activity by regulating Th1/Th2, reducing oxidative stress, preserving intestinal barrier integrity, & inhibiting TLR4/MAPK/NF-κB pathway. Selon Ni L (2022) : Ulcerative colitis is a chronic inflammatory bowel disease (IBD) with a low cure rate.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Len Worthington without modification (CC BY-SA 2.0). License : CC BY-SA 2.0.