Porophyllum ruderale (Lawnika – savann’) : medicinal properties in alcoholic extraction

Porophyllum ruderale (Lawnika – savann’) — family Asteracées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The monograph draws on 36 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Oxidative stress : Plant part used: Sheet. Documented pharmacological profile: Quercétine-like.
   Selon Dzigbor A (2025) : Dzigbor A et al, total phenolic content, antioxidant activity, GC-MS characterization, & antimicrobial activity of leaf & flower extracts of Porophyllum ruderale, Pharmacol Res-Nat prod, 7-100243, 2025-Abstract:. Selon Conde-Hernandez LA (2014) : The fresh pepper leaf extract, obtained using ultrasound as the extraction method contained the highest amount of antioxidant activity. Total phenolic compounds and antioxidant activity were evaluated with the phenol Folin Ciocalteu reagent and the ABTS method, respectively.
2. Metastatic melanoma of the lung : Plant part used: Aerial parts. Documented pharmacological profile: Doxorubicine-like.
   Selon Kato da Silva B (2021) : The aim of this study was to evaluate the Porophyllum ruderale effects on the liver in murine melanoma model B16-F10 & to determine the antioxidant potential. Although a significant antioxidant activity was verified for the two concentrations analyzed, they were not sufficient to minimize the melanoma effects toxic in the mice liver as observed by histological changes & that leads us to conclude that the hydroalcoholic extract of aerial parts of PR, in the concentrations used, possesses antioxidant properties, good performance in inhibiting the proliferation of human melanoma cells, but it has no hepatoprotective effect in the melanoma cutaneous treatment,.
3. Wound, burn : Plant part used: Sheet. Mentioned synergistic association: Laser Ingap-670.
   Selon Vasquez-Atanacio MJ (2021) : These studies were carried on the extracts & isolated com- pounds and support most of their reported uses in folk medicine as antifungal, antileishmanial, anti-inflammatory, anti-nociceptive & burn repair activities, & as a potential source of new class of insecticides.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Wibowo Djatmiko without modification (CC BY 4.0). License : CC BY 4.0.