Solanum americanum (Agouman) : medicinal properties in alcoholic extraction

Solanum americanum (Agouman) — family Solanacées.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 21 indications in alcoholic extraction for this species. The monograph draws on 319 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Fruit. Documented pharmacological profile: Doxorubicine-like. Mentioned synergistic association: Doxorubicine.
   Selon Winkiel M (2022) : Among others, GAs exhibit significant antitumor properties, for example, a strong inhibitory effect on cancer cell growth. This activity can result in the induction of tumor cell apoptosis, which can occur via different molecular pathways. Selon Luo S (2000) : This article summarizes the research progress of the antitumor effect and mechanism of solanine over the past 20 years, to provide a reference for workers in the field of cancer research.
2. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Chloramphénicol-like.
   (1993) : In vitro antibacterial studies on the leaf extracts were carried out on selected bacterial strains Staphylococcus aureus, Bacillus subtilis, Salmonella typhi, Klebsiella pneumonia, using disc diffusion assay. Selon Ramya S (2012) : In vitro antibacterial studies on the leaf extracts were carried out on selected bacterial strains Staphylococcus aureus, Bacillus subtilis, Salmonella typhi, Klebsiella pneumonia, using disc diffusion assay.
3. Liver disorders : Plant part used: Fruit. Documented pharmacological profile: Silymarine-like.
   Selon Chester K (2019) : nigrum & to explore their hepatoprotective potential. is well known for the management of different ailments including hepatic disorders. M (2008) : The results showed that the treatment of SNE significantly lowered the CCl4-induced serum levels of hepatic enzyme markers (GOT, GPT, ALP, & total bilirubin), superoxide & hydroxyl radical.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by David Eickhoff without modification (CC BY 4.0). License : CC BY 4.0.