Swietenia mahogani (Mahogani-ti-fèy) : medicinal properties in alcoholic extraction

Swietenia mahogani (Mahogani-ti-fèy) — family Méliacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 13 indications in alcoholic extraction for this species. The monograph draws on 47 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: Seed. Documented pharmacological profile: Vancomycine-like.
   Selon Al-alusi1 NT (s.d.) : This study has carried out to evaluate the antibacterial effect & the interaction between Tinospora crispa & Swietenia Mahogani extracts against resistant strains of Methicillin-resistant Staphylococcus aureus (MRSA). Mahogani extracts were assayed to determine their antibacterial activity against eight clinical MRSA isolates. Selon UDOUMOH AF (2011) : Different concentrations of ethanolic extracts of Swietenia Mahogani & Carapa procera leaves were evaluated for antibacterial activity against Staphylococcus aureus ATCC25923, Escherichia coli ATCC 25922, & Pseudomonas aeruginosa ATCC 27853 using the agar well diffusion method.
2. Gastric ulcer : Plant part used: Seed. Documented pharmacological profile: Oméprazole-like.
   Selon Al-Radahe S (2013) : Mahogani ethanol leaf extract exhibit an Antiulcer activity against ethanol-induced gastric ulcer in experimental animals. Histological studies of the gastric Wall of ulcer control group revealed severe damage of gastric Mucosa, along with edema & leucocytes infiltration of the submucosal layer compared to rats received either omeprazole or S. Selon Alrdahe SS (2010) : Present study was performed to evaluate anti-ulcerogenic activity of ethanol seed extract against ethanol induced gastric mucosal injury in rats.
3. Cancer : Plant part used: Seed. Documented pharmacological profile: Vincristine-like.
   Selon Matsuse T (1998) : For the purpose of finding anti-HIV agents from natural sources, various plant extracts were screened for their inhibitory activity against HIV-protease, an enzyme essential for viral proliferation. Selon Sivanandan RN (2016) : Sivanandan RN et al, ANTI – SALMONELLA ACTIVITY AND CYTOTOXICITY STUDIES ON THE METHANOLIC LEAF EXTRACT OF SWIETENIA MAHAGONI, Indo Am J of Pharmaceut Res, 2016,.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by David J. Stang without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.