Tanacetum parthenium (Tanézi) : medicinal properties in alcoholic extraction

Tanacetum parthenium (Tanézi) — family Asteracées.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The monograph draws on 72 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Aerial parts. Mentioned synergistic association: Paclitaxel.
   Selon He X (2011) : He X et al, Resveratrol enhances the antitumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling. Selon Parada-Turska J (2007) : In this study, we determined the effect of parthenolide on proliferation of three human cancer cell lines: human lung Carcinoma (A549), human medulloblastoma (TE671), human colon adenocarcinoma (HT-29) & human umbilical vein endothelial cells (HUVEC) in vitro. Moreover, the anticancer potential of this compound was suggested.
2. Pain, hyperalgesia : Plant part used: Aerial parts. Documented pharmacological profile: Ibuprofène-like, Morphine-like, Nimusolide-like.
   Selon Asgari A (2013) : Group receiving a dose of 40 mg/kg extract had higher antinociceptive effects than the group receiving Ibuprofen (p<0.001) but it didn't have any significant difference with the group receiving morphine. Animals were injected with 0.9% acetic acid for visceral pain induction. Selon Safakhah HA (2017) : Results: CCI led to mechanical allodynia & thermal hyperalgesia.
3. Hyperalgesia : Plant part used: Aerial parts.
   Selon Safakhah HA (2017) : Results: CCI led to mechanical allodynia & thermal hyperalgesia. Conclusion: Chronic orally used TP extract alleviates CCI-induced neuropathic pain in male rats. Selon Asgari A (2013) : Animals were injected with 0.9% acetic acid for visceral pain induction.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

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