Momordica dioica (Qwo Pawoka) : vertus médicinales en extraction alcoolique

Momordica dioica (Qwo Pawoka) — famille Cucurbitacées.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 13 indications en extraction alcoolique pour cette espèce. La monographie s’appuie sur 51 références scientifiques enregistrées pour l’espèce.

Indications thérapeutiques en extraction alcoolique :

Note : les extraits de références scientifiques sont conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction, afin de respecter le texte source des publications.

1. Troubles hépatiques : Partie usitée : Racine. Profil pharmacologique documenté : Silymarine-like.
   Selon Kushwaha SK (2005) : The fraction caused decrease in serum level of enzymes serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase, alkaline phosphate & total bilirubin in treated rats as compared to control. The flavonoidal fraction collected from column chromatography from ethanolic extract of fruits of Momordica dioica Roxb was evaluated for hepatoprotective activity in Wistar strain of albino rats of either sex against carbon tetrachloride induced hepatic damage. Selon Ilango K (2004) : The extracts, at a dose of 400 mg/kg (po) administered for 7 days exhibited a significant therapeutic effect by lowering Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum Glutamate Pyruvate Transaminase (SGPT), serum alkaline phosphatase (ALP) & serum bilirubin & increasing the serum levels.
2. Stress oxydatif : Partie usitée : Fruit. Profil pharmacologique documenté : Acide ascorbique-like, alpha-tocophérol-like.
   Selon Nandini HS (2020) : The results from in vitro studies and both the extracts have potent antioxidant & free radical scavenging properties. The extraction was submitted to the in vivo cardioprotective activity by stress & clozapine-induced cardiotoxicity by using hypoglycaemic rats. Selon Vijayakumar M (2011) : Estimation of H+-K+ ATPase activity & gastric wall mucous were performed in ethanol-induced ulcer model, antioxidant enzyme activities was carried out in cold-restraint stress-induced ulcer model, & various gastric secretion parameters like volume of gastric juice, acid output, & pH value were estimated in pylorus ligation-induced ulcer model.
3. Arthrose, arthrite, rhumatisme, oedème : Partie usitée : Racine. Profil pharmacologique documenté : Ibuprofène-like.
   Selon Shreedhara CS (2006) : The alcoholic extract also significantly reduced carrageenan-induced paw edema when administered orally (200 mg/kg) & the activity was comparable with ibuprofen (200 mg/kg, p.o.). Selon Rakh MS (2011) : The present study sought to determine, in more detail, the effects of various extracts of Momordica dioica seed for anti cataleptic activity as the plant is having antiasthamatic activity.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et le détail des références scientifiques sont disponibles dans la fiche monographique complète.

Crédit photo : Photo de Dinesh Valke sans modification (CC BY 4.0). Licence : CC BY 4.0.