Piper nigrum (Pwèv-nwè) : vertus médicinales en extraction alcoolique

Piper nigrum (Pwèv-nwè) — famille Piperacées.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 25 indications en extraction alcoolique pour cette espèce. La monographie s’appuie sur 93 références scientifiques enregistrées pour l’espèce.

Indications thérapeutiques en extraction alcoolique :

Note : les extraits de références scientifiques sont conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction, afin de respecter le texte source des publications.

1. Infection bactèrienne : Partie usitée : Feuille. Profil pharmacologique documenté : streptomycine-like.
   Selon Manjukeswari S (2013) : The present study aimed at evaluating the antibacterial activity of ethanolic extracts of leaves of Piper nigrum, Piper longum & Adhatoda vasica against Streptococcus mutans, Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae. The results revealed that the ethanolic extract of leaf presented the highest zone of inhibition in B subtilis, S mutans. Selon Ertuk O (2011) : Eleven ethanolic extracts from spices of Melissa officinalis(FR:FE), Mentha piperita((Se), Laurus nobilis(Fe), Rhus coriaria, Dianthus coryophyllum, Piper nigrum(Se), Capsicum annum (Fr), Juniperus oxycedrus, Erica arborea, Colutea arborescens, & Cuminum cyminum(Fr) collected from various regions of Turkey & local markets were assayed for the in vitro antibacterial activity against 3 Gram-positive (Bacillus subtilis, Staphylococcus aureus & S.
2. Traitement adjuvant de la maladie d’Alzheimer : Partie usitée : Fruit. Profil pharmacologique documenté : Donepezil-like. Association synergique mentionnée : Myristica fragans, Syzygium aromaticum.
   Selon Cheng C (2020) : On the basis of the activities of its individual components, KBD could have good potential for the treatment of Alzheimer's disease (AD). Selon Chonpathompikunlert P (2010) : Based on this information, the effect of piperine, a main active alkaloid in fruit of Piper nigrum, on memory performance & neurodegeneration in animal model of Alzheimer's disease have been investigated. Recently, numerous medicinal plants possessing profound central nervous system effects & antioxidant activity have received much attention as food supplement to improve cognitive function against cognitive deficit condition including in Alzheimer's disease condition.
3. Cancer : Partie usitée : Fruit. Profil pharmacologique documenté : Méthotrexate-like.
   Selon Turrini E (2020) : The main limits of current anticancer therapy are relapses, chemoresistance, & toxic effects resulting from its poor selectivity towards cancer cells that severely impair a patient's quality of life. The present review aims to provide a comprehensive overview of the anticancer potential of PN & its major active constituents-not limited to the well-known piperine-whose undeniable anticancer properties have been reported for different cancer cell lines & animal models. Selon Pratibha N (2004) : These results demonstrate that this novel polyherbal formulation is a potent anti-inflammatory agent that can ameliorate the symptoms of allergic rhinitis.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et le détail des références scientifiques sont disponibles dans la fiche monographique complète.

Crédit photo : Photo de David J. Stang sans modification (CC BY-SA 4.0). Licence : CC BY-SA 4.0.