Acalypha wilkesiana (Jipon-kankan) : medicinal properties in alcoholic extraction

Acalypha wilkesiana (Jipon-kankan) — family Euphorbiacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 17 indications in alcoholic extraction for this species. The monograph draws on 32 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Fungal infection : Plant part used: aerial parts. Documented pharmacological profile: Clotrimazole-like (Crème).
   According to Fawehinmi AB (2019): The antifungal results are in the increasing order Microsporum audounii = Epidermophyton floccosum < M. furfur < Trichophyton mentagrophytes. According to AZUBUIKE CP (2013): wilkesiana has both antibacterial & anticandidal activity & also has high potential as antimicrobial agent when formulated as ointment topical use.
2. Bacterial infection : Plant part used: aerial parts.
   According to AZUBUIKE CP (2013): The MIC values of the extract against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa & Candida albicans were 5.00, 1.25, 10.00 & 5.00 mg/ml respectively. The zones of inhibition (mm) of the extract on the growth of the microorganisms were Escherichia coli (25.2 ± 1.0), Staphylococcus aureus (28.1 ± 0.5), Pseudomonas aeruginosa (32.4 ± 0.4) & Candida albicans (22.4 ± 1.3) but there was no zone of inhibition for Aspergillus flavus & Penicillium notatum. According to Awe FA (n.d.): The identified bacterial pathogen includes Streptococcus sp, Bacillus Cereus, Klebsiella sp, Enterobacter aerogenes and Escherichia coli.
3. Infections in catfish (Clarias gariepinus) : Plant part used: Sheet. Documented pharmacological profile: Gentamycine-like.
   According to Awe FA (n.d.): The identified bacterial pathogen includes Streptococcus sp, Bacillus Cereus, Klebsiella sp, Enterobacter aerogenes and Escherichia coli. The leaves of these plants have inhibitory action on isolated bacteria & can be used to treat bacterial fin-rot of infected catfish Clarias gariepinus. According to AZUBUIKE CP (2013): The preliminary in vitro antimicrobial activity of the extract at concentrations of 2.5 mg/ml, 5 mg/ml and 10 mg/ml and those of the ointments was determined against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, Aspergillus flavus & Penicillium notatum using the agar cup plate method.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo de Krzysztof Ziarnek, Kenraiz sans modification (CC BY 4.0). License : CC BY 4.0.