Christia vestertillionis (Zèl-papiyon) : medicinal properties in alcoholic extraction

Christia vestertillionis (Zèl-papiyon) — family Fabacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The monograph draws on 48 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Mentioned synergistic association: Cyclophosphamide.
   According to Hofer D (2013): In an attempt to find new therapeutic plant extracts of Christia vespertilionis (CV) their antitumor potential in human medullary thyroid carcinoma (MTC) & human small intestinal neuroendocrine tumor (SI-NET) cell lines were tested. CV extracts showed antiproliferative & proapoptotic effects in all MTC & SI-NET cell lines, whereby high growth inhibition was observed by treatment with the ethylacetate-extracts (CV-45) in tumor cell lines but not in normal human fibroblasts. According to Lee JJ (2020): The cytotoxic effects were determined using MTT assay against human breast carcinoma cell lines (MCF-7 & MDA-MB-231).
2. Oxidative stress : Plant part used: Sheet. Documented pharmacological profile: Quercétine-like.
   According to Ibrahim Farrah S (2022): Results show that to date, phytochemicals such as alkaloids, flavonoids, quinones, & others have been identified, corresponding to its range of pharmacological activities that include anti-cancer, anti-malaria, & antioxidant. According to Author (2017): The percentage of inhibition in antioxidant showed that ethyl acetate extract was the highest & SFE without ethanol co-solvent the lowest. The antioxidant activity on the extracts were tested using free radical scavenging activity of 1,1-diphenyl-2-picrilhydrazyl (DPPH) assay as well as to determine phytochemical components, alkaloid & flavonoid using the suitable chemical tests.
3. Osteoarthritis, arthritis, rheumatism, oedema : Plant part used: Sheet.
   According to Zambari IF (2023): This study aims to compare & analyze the anti-inflammatory properties & activities of green and red C. vespertilionis types have the potential to act as anti-inflammatory agents, but green leaves are preferable. According to Osman M.S (2017): The findings of this study indicates the global yield of the MCV oils is 31 mg/g while the compound identification indicates the presence of anti-cancer, anti-inflammatory & beneficial phytochemicals.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Strange Wonderful Things without modification (CC BY 4.0). License : CC BY 4.0.