Cucumis melo (Milon) : medicinal properties in alcoholic extraction

Cucumis melo (Milon) — family Cucurbitacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 23 indications in alcoholic extraction for this species. The monograph draws on 103 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Obesity, metabolic syndrome : Plant part used: Fruit.
   According to Lee D (2018): Simultaneously, the microbiota composition ratios changed. We also profiled the gut microbiota to determine whether the ratios of microbial phyla changed. According to Parmar HS (2008): the peel extracts of Mangifera indica (MI), Cucumis melo (CM) & Citrullus vulgaris (CV) fruits in ameliorating the diet-induced alterations in dyslipidemia, thyroid dysfunction and diabetes mellitus have been investigated in rats.
2. Cancer : Plant part used: Fruit. Documented pharmacological profile: Cyclophosphamide-like.
   According to Rolim PM (2018): To assess the antiproliferative potential in human cancer cell lines, such as kidney carcinoma, colorectal carcinoma, cervical adenocarcinoma & cervical carcinoma, MTT assay was performed. The proliferation was inhibited by 20–85% at extracts concentrations of 0.1–1.0 mg/mL in all cancer cell lines. According to Vidya R (2021): Wistar rats were divided into six groups and hepatic cancer was induced with 0.01 % DEN (diethylnitrosamine) through drinking water for 16 weeks.
3. Oxidative stress : Plant part used: Fruit. Documented pharmacological profile: Acide ascorbique-like, acide gallique-like.
   According to Ali M (2019): The objective of this study was to investigate the role of Cucumic melo var agrestis, Vitamin C & zinc on human spermatozoa & oxidative stress during cryopreservation in astheno-zoospermia. The oral administration of antioxidant combination of CM, vitamin C & zinc improves sperm characteristics in astheno-zoospermia. According to Author (2016): Phenolic composition of different extracts of honeydew melon seeds & their antioxidant activity was determined for the first time.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Zenon Sych without modification (CC BY 4.0). License : CC BY 4.0.