Hedychium coronarium (White lavender) : medicinal properties in alcoholic extraction

Hedychium coronarium (White lavender) — family Zingiberacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The monograph draws on 96 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Rhizome. Documented pharmacological profile: Campothécine-like.
   Selon Bailly C (2020) : Recently, different studies have underlined the anticancer activities of CRD & in particular its capacity to inhibit the growth and to induce the death of glioblastoma & carcinoma cell lines in vitro. The anticancer properties of several labdane diterpenes have been well characterized, notably for andrographolide & sclareol. Selon Donipati P (2015) : The purpose of this study was to test in vitro anticancer activities of the hexane, chloroform & methanolic extracts of Hedychium coronarium against the human breast cancer cell lines [MCF-7].
2. Type II diabetes mellitus : Plant part used: Sheet. Documented pharmacological profile: Glibenclamide-like, Metformine-like.
   Selon Rakesh Barik (2015) : Ethanolic extract (250 and 500 mg/kg body weight) was administered orally to streptozotocin induced type II diabetic male Wistar albino rats. Koenig (Zingiberaceae) in streptozotocin induced diabetic rats. Selon Pranitha K (2014) : Pranitha K et al, Hypoglycemic effect of ethanolic extract of Hedychium coronarium Linn rhizome in alloxan induced diabetes in rat model, Inter J Res Pharm & Pharmacol, 3 :3, 2014-Abstract To study the Hypoglycemic effect of ethanolic extract of Hedychium coronarium Linn., rhizome in Alloxan induced diabetes in rat model.
3. Trypanosomiasis : Plant part used: Essential oil. Mentioned synergistic association: Pentamidine (rhizome).
   Selon Rodrigues DF (2013) : Essential oils & major components were tested for trypanocidal activity using procyclic forms of Trypanosoma brucei (427 & 29-13 strains). brucei strains (CI50 = 65.77 μg·mL−1 & 24.53 μg·mL−1, resp.), & the synergism between caryophyllene oxide/plus Pentamidine (1: 1, v/v) highly increased the trypanocidal activity (<1.0 μg·mL−1).

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Nasser Halaweh without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.