Pometia pinnata (Kava) : medicinal properties in alcoholic extraction

Pometia pinnata (Kava) — family Sapindacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 17 indications in alcoholic extraction for this species. The monograph draws on 53 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Hypertension : Plant part used: Sheet. Documented pharmacological profile: Furosémide-like.
   Selon Elisa N (2020) : The hypertension profile observed in this study was the blood volume of rats. Hypertension is a problem of cardiovascular disease that occurs in many people. Selon Purwidyaningrum I (2016) : The effective dose of ethanolic matoa leaves extract for diuretic activity was 100 mg/kg bw which could increase the excretion of sodium & potassium in the urine of the male Wistar rats.
2. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Chloramphénicol-like.
   Selon Auteur (2022) : Objective: This study aims to determine the antibacterial activity of the ethanolic extract of PP leaves against Staphylococcus aureus & Pseudomonas aeruginosa bacteria. The results of the phytochemical screening of dried powder & the ethanolic extract of PP leaves contain secondary metabolites of flavonoids, alkaloids, tannins, saponins, glycosides, and steroids The ethanol extract of matoa leaves has the lowest inhibitory concentration of 1 mg/ml against Staphylococcus aureus & Pseudomonas aeruginosa with diameters of 8.00 mm & 8.50 mm, respectively, and the effective concentration was 50 mg/ml with diameters of 14.10 mm & 14.30 mm. Selon Triana A (2020) : Triana A et al, Supplementation of matoa (Pometia pinnata) leaf extract & alginate suppressed the growth of Staphylococcus aureus & Escherichia coli in pasteurized milk.
3. Liver disorders : Plant part used: Sheet. Documented pharmacological profile: Silymarine-like.
   Selon Adrian A (2021) : RESULTS: The effect of extract ethanol of PP on liver injury biochemical markers AST, ALT, LDH, & total protein. CONCLUSION: In summary, extract ethanol of PP has hepatoprotective effect by reducing the level of AST, ALT, total protein, & LDH levels. Selon Sihotang y (2017) : Hepatoprotective effect was studied by measuring the level of AST, ALT, ALP & total protein in serum.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Forest and Kim Starr without modification (CC BY 4.0). License : CC BY 4.0.